ALPHA MAN

Media

Miscellaneous Media

• April 2011: Listen to an Interview with Paul Saftig on Deutschlandfunk radio station (German, MP3, 4 min)

 

Press releases

• December 2012: Zymenex Press Release: Zymenex in Phase 3 clinical trial in patients with the rare disease alpha-Mannosidosis. (PDF file, English)
  
  
• October 2011: Zymenex Press Release (US & UK): Positive clinical effect in Phase 2 trial in patients with the rare disease alpha-Mannosidosis. (PDF file, English)
  
  
• June 2011: Labor & More magazine - Von Mäusen zu Menschen (article about α-Mannosidosis and the Alpha Man project, PDF file, German)

• April 2011: Frederiksborg Amts Avis - Article about the project (PDF file, Danish)
  
  
• April 2011: Interview with Paul Saftig on Deutschlandfunk radio station (German)
  
  
• Jan 2011: Press clipping: Frankfurter Allgemeine Zeitung - Therapie für Mannosidose in Sicht (PDF file, German)
  
  
• Jan 2011: Press clipping: Mainzer Allgemeine Zeitung - Therapie klinisch testen. (JPG file, German)
  
  
• Dec 2010: Bionity.com - Therapie für unheilbare Kinderkrankheit in Sicht (PDF file, German)
  
  
• Dec 2010: Press articles overview (PDF file, German/English)
  
  
• Dec 2010: Therapie für unheilbare Kinderkrankheit in Sicht (Kieler Nachrichten vom 9.12.2010)
  
  
• Dec 2010: Therapy for incurable childhood diseases is in sight
  
  
• Dec 2010: Zymenex enzyme gets EU-millions for clinical trials in ALPHA-MAN project
  

 

Publications

• Borgwardt, L., Dali, C., Fogh, J., Månsson, J.E., Olsen, K.J. , Beck, H.C., Nielsen, K.G., Nielsen, L.H., Olsen, S.O.E., Stensland, H.M., Nilssen, Ø., Wibrandt, F., Thuesen, A.M., Pearl, T., Haugsted, U., Saftig, P., Blanz, J., Lund, A.M. (2013)
  Enzyme Replacement Therapy for alpha-mannosidosis: 12 months follow-up of a single centre, randomized, multiple dose study. (PDF file)
  J. Inherit. Met. Dis., in press
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• Malm D, (Updated 2012). Reviewer: Alpha-Mannosidosis. In: Rare Disease Database. Copyright 2012, National Organization for Rare Disorders (NORD). Available at http://www.rarediseases.org
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• Avenarius DF, Svendsen JS, Malm D Proton nuclear magnetic resonance spectroscopic detection of oligomannosidic n glycans in alpha-mannosidosis: a method of monitoring treatment. (PDF file). J. Inherit. Metab. Diss. 2011 Oct;34(5):1023-7.
  
  
• M Mynarek, J Tolar, MH Albert, ML Escolar, JJ Boelens, MJ Cowan, N Finnegan, A Glomstein, DA Jacobsohn, JS Kühl, H Yabe, J Kurtzberg, D Malm, PJ Orchard, C Klein, T Lücke and K-W Sykora Allogeneic hematopoietic SCT for alpha-mannosidosis: an analysis of 17 patients. (PDF file). Bone Marrow Transplantation 2012 Mar;47(3):352-9.
  
  
• Damme, M., Stroobants, S., Walkley, S., Lüllmann-Rauch, R., D’Hooge, R., Fogh, J., Saftig, P., Lübke, T., Blanz, J. (2010) Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in alpha-mannosidosis. J Neuropathol Exp Neurol. 2011 Jan;70(1):83-94.